利用抗血管紧张素II血清进行沙拉新的放射免疫测定。

Radioimmunoassay for saralasin by means of anti-angiotensin II sera.

作者信息

Kappelgaard A N, Ibsen H, Nielsen M D, Giese J

出版信息

Clin Chim Acta. 1978 Feb 1;83(1-2):25-31. doi: 10.1016/0009-8981(78)90202-4.

PMID:620465

Abstract

A radioimmunoassay for the angiotensin II-inhibitor saralasin has been developed. The assay is based upon an exploitation of the cross-reactivity of antisera raised against angiotensin II, with radioiodinated saralasin as the tracer peptide. Performance data for the assay and results obtained in clinical infusion studies are presented.

摘要

已开发出一种用于血管紧张素II抑制剂沙拉新的放射免疫测定法。该测定法基于利用针对血管紧张素II产生的抗血清与放射性碘化沙拉新作为示踪肽的交叉反应性。文中给出了该测定法的性能数据以及在临床输注研究中获得的结果。