普萘洛尔在人体中的处置的生物学决定因素。 - Suppr

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Biological determinants of propranolol disposition in man.

作者信息

Kornhauser D M, Wood A J, Vestal R E, Wilkinson G R, Branch R A, Shand D G

出版信息

Clin Pharmacol Ther. 1978 Feb;23(2):165-74. doi: 10.1002/cpt1978232165.

DOI:10.1002/cpt1978232165

PMID:620476

Abstract

摘要

相似文献

Biological determinants of propranolol disposition in man.普萘洛尔在人体中的处置的生物学决定因素。

Clin Pharmacol Ther. 1978 Feb;23(2):165-74. doi: 10.1002/cpt1978232165.

Effect of thyrotoxicosis on liver blood flow and propranolol disposition after long-term dosing.长期给药后甲状腺毒症对肝血流量和普萘洛尔处置的影响。

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Food effects on propranolol systemic and oral clearance: support for a blood flow hypothesis.食物对普萘洛尔全身清除率和口服清除率的影响：对血流假说的支持。

Clin Pharmacol Ther. 1986 Oct;40(4):408-14. doi: 10.1038/clpt.1986.198.

Direct measurement of propranolol bioavailability during accumulation to steady-state.在达到稳态蓄积过程中对普萘洛尔生物利用度的直接测定。

Br J Clin Pharmacol. 1978 Oct;6(4):345-50. doi: 10.1111/j.1365-2125.1978.tb00862.x.

Bioavailability of propranolol in the dog.普萘洛尔在犬体内的生物利用度。

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Disposition of propranolol. V. Drug accumulation and steady-state concentrations during chronic oral administration in man.普萘洛尔的处置。V. 人体长期口服给药期间的药物蓄积和稳态浓度。

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Dose-dependent disposition of oral propranolol in normal subjects.正常受试者口服普萘洛尔的剂量依赖性处置。

Biopharm Drug Dispos. 1980 Apr-Jun;1(4):159-66. doi: 10.1002/bdd.2510010403.

No stereoselective first-pass hepatic extraction of propranolol.普萘洛尔不存在肝脏首过效应的立体选择性提取。

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Clinical pharmacokinetics of propranolol.普萘洛尔的临床药代动力学

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Pharmacokinetics of propranolol during pregnancy.普萘洛尔在孕期的药代动力学。

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Development and Evaluation of a Physiologically Based Pharmacokinetic Drug-Disease Model of Propranolol for Suggesting Model Informed Dosing in Liver Cirrhosis Patients.开发和评估普萘洛尔基于生理学的药代动力学药物-疾病模型，以建议肝硬化患者的模型指导剂量。

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Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties.含盐酸普萘洛尔的粘膜粘附性明胶口腔膜：机械性能、粘膜粘附性及生物药剂学性质评估

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PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol.PKQuest：一种基于生理学的通用药代动力学模型。普萘洛尔的介绍与应用

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Time-dependent modifications of splanchnic circulation in female pigs submitted to end-to-side portacaval anastomosis.接受端侧门腔静脉吻合术的雌性猪内脏循环的时间依赖性改变。

Dig Dis Sci. 2001 Mar;46(3):489-94. doi: 10.1023/a:1005678627599.

Effect of food intake on pharmacokinetics of oral artemisinin in healthy Vietnamese subjects.食物摄入对健康越南受试者口服青蒿素药代动力学的影响。

Antimicrob Agents Chemother. 1997 May;41(5):1069-72. doi: 10.1128/AAC.41.5.1069.

The effect of oxprenolol dosage time on its pharmacokinetics and haemodynamic effects during exercise in man.心得平给药时间对人体运动期间其药代动力学及血流动力学效应的影响。

Eur J Clin Pharmacol. 1993;44(2):171-6. doi: 10.1007/BF00315476.

Individual variation in first-pass metabolism.首过代谢的个体差异。

Clin Pharmacokinet. 1993 Oct;25(4):300-28. doi: 10.2165/00003088-199325040-00005.

Assessment of liver metabolic function. Clinical implications.肝脏代谢功能评估。临床意义。

Clin Pharmacokinet. 1994 Sep;27(3):216-48. doi: 10.2165/00003088-199427030-00005.

Influence of vitamin C on the absorption and first pass metabolism of propranolol.维生素C对普萘洛尔吸收及首过代谢的影响。

Eur J Clin Pharmacol. 1995;48(3-4):295-7. doi: 10.1007/BF00198315.

Propranolol disposition in renal failure.肾衰竭时普萘洛尔的处置

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