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[因滥用鼻喷雾剂导致盐皮质激素过量引起的动脉高血压。病例报告]

[Arterial hypertension induced by an excess of mineralocorticoids caused by abuse of nasal spray. Report of a case].

作者信息

De Venuto G, Mattarei M, Dal Piaz A, De Santa A, Torboli P L, Miori R

出版信息

Minerva Med. 1984 Jun 30;75(27):1673-77.

PMID:6205328
Abstract

Among the various syndromes caused by excess mineralocorticoids, the factitious syndrome produced by excessive 9-alpha-fluorprednisolone inhalations is more common than might be expected, especially in places where the drug is easily obtained without a doctor's prescription. A fairly typical case of addiction to a nasal spray containing ephedrine hydrochloride and an imidazoline compound as well as the steroid is described. The diagnosis of the case is analysed with details of certain differences from similar cases reported in the literature and the modifications to clinical and instrumental parameters achieved after over two months' treatment with spironolactone are described.

摘要

在由过多盐皮质激素引起的各种综合征中,因过量吸入9-α-氟泼尼龙导致的人为综合征比预期更为常见,尤其是在无需医生处方就能轻易获得该药物的地方。本文描述了一例对含有盐酸麻黄碱、一种咪唑啉化合物以及该类固醇的鼻喷雾剂上瘾的相当典型的病例。分析了该病例的诊断情况,并详细说明了与文献中报道的类似病例的某些差异,还描述了使用螺内酯治疗两个多月后临床和仪器参数的变化。

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