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[人白细胞β2-唾液酸球蛋白(RAL-6)的免疫化学鉴定及物理化学特性]

[Immunochemical identification and physicochemical characteristics of human leukocytic beta 2-sialoglobulin (RAL-6)].

作者信息

Petrunin D D, Lopukhin Iu M, Olefirenko G A

出版信息

Biull Eksp Biol Med. 1984 Jul;98(7):75-6.

PMID:6205702
Abstract

A new glycoprotein (RAL-6) was identified in human venous blood by immunochemical assay. During studies into the physicochemical properties, it was established that the glycoprotein has a mobility of beta 2-globulins and contains sialic acids. Study of RAL-6 content in tissue extracts from different organs of man and in biological fluids demonstrated the protein to be contained by pus extracts in a large quantity. The concentration of RAL-6 in hemolysates was found to be lowered in some of the diseases including those of the autoimmune nature.

摘要

通过免疫化学分析在人静脉血中鉴定出一种新的糖蛋白(RAL-6)。在对其理化性质的研究过程中,确定该糖蛋白具有β2球蛋白的迁移率且含有唾液酸。对人体不同器官的组织提取物和生物体液中RAL-6含量的研究表明,脓液提取物中含有大量该蛋白。发现在包括自身免疫性疾病在内的一些疾病中,溶血产物中RAL-6的浓度会降低。

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