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[用聚明胶肽和全氟碳乳剂连续替代犬失血性休克的实验研究]

[Successive replacement of fatal blood loss in dogs with polyglucin and perfluorocarbon emulsion].

作者信息

Akhsianov U U, Afonin N I

出版信息

Biull Eksp Biol Med. 1984 Aug;98(8):160-2.

PMID:6205706
Abstract

The authors studied the hemodynamics and gaseous exchange in dogs after successive replacement of lethal hemorrhage (50 ml/kg bw) by polyglucin and perfluorocarbon emulsion (24 vol/%). The main hemodynamic parameters got recovered and were maintained at the level approaching the initial one during the entire observation period. After blood replacement the pO2 in the artery rose to 500 mmHg, that in the vein to 120 mmHg. The oxygen volume in the blood increased by 3 vol/% on the average. Oxygen consumption also rose. All the animals survived.

摘要

作者研究了用聚葡萄糖和全氟碳乳剂(24体积/%)连续替代致死性出血(50毫升/千克体重)后犬的血流动力学和气态交换情况。在整个观察期内,主要血流动力学参数得以恢复并维持在接近初始水平。输血后动脉血氧分压升至500毫米汞柱,静脉血氧分压升至120毫米汞柱。血液中的氧含量平均增加了3体积/%。氧耗量也增加。所有动物均存活。

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