Invasion of lumbosacral ventral roots and spinal pia mater by substance P-immunoreactive axons after sciatic nerve lesion in kittens.

An indirect immunohistochemical technique was used to identify substance P immunoreactive nerve fibers in the ventral roots and spinal pia mater in kittens previously subjected to sciatic nerve lesion. It was shown that the ipsilateral L7 ventral root and spinal pia mater was invaded by substance P immunoreactive nerve fibers after the nerve lesion.