Sumi Y, Koyama Y, Muraki T, Suzuki T
Basic Appl Histochem. 1984;28(2):137-42.
In the continuous research for a more sensitive chelator for cadmium, thiazolylazoalkylaminophenol derivatives were synthesized. The staining sensitivity for cadmium and molar absorptivity of their cadmium chelates were examined. Though the molar absorptivity of bromothiazolylazodiethylaminophenol(Br-TADA)-cadmium chelate demonstrated an order of 10(5), the staining sensitivity of Br-TADA was unexpectedly low. The lowering of the sensitivity of Br-TADA may be attributed to alkaline hydrolysis and a decrease in the stability constant of the cadmium chelate.
在对更灵敏的镉螯合剂进行持续研究的过程中，合成了噻唑基偶氮烷基氨基酚衍生物。研究了它们的镉螯合物对镉的染色灵敏度和摩尔吸光系数。尽管溴噻唑基偶氮二乙氨基酚（Br-TADA）-镉螯合物的摩尔吸光系数显示为10⁵数量级，但Br-TADA的染色灵敏度却出乎意料地低。Br-TADA灵敏度降低可能归因于碱性水解以及镉螯合物稳定常数的降低。
