Conte N, Repetti R, Testa D, Barbero P, Voltolina P, Diani F
Boll Soc Ital Biol Sper. 1984 Jul 31;60(7):1453-6.
Maternal plasma alpha-fetoprotein (AFP) was measured in fifteen women during first-mid-third-trimester of pregnancy. In three of these pregnacies by means ultrasound was relevable a condition of intrauterine growth retardation (IUGR). AFP was assayed by a double-antibody radioimmunoassay and values were compared with the median value of the normal range for the particular week of pregnancy. Plasma AFP levels were significantly higher in one subject with IUGR than in other patients.
在15名女性妊娠的早、中、晚期测量了母血甲胎蛋白(AFP)。在其中3例妊娠中,通过超声检查发现存在宫内生长迟缓(IUGR)情况。采用双抗体放射免疫分析法检测AFP,并将检测值与妊娠特定孕周正常范围的中位数进行比较。1例IUGR患者的血浆AFP水平显著高于其他患者。