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猫基底前脑神经元在睡眠-觉醒周期中的放电特性。

Firing properties of cat basal forebrain neurones during sleep-wakefulness cycle.

作者信息

Détári L, Juhász G, Kukorelli T

出版信息

Electroencephalogr Clin Neurophysiol. 1984 Oct;58(4):362-8. doi: 10.1016/0013-4694(84)90062-2.

DOI:10.1016/0013-4694(84)90062-2
PMID:6207005
Abstract

Neuronal activity was studied in the basal forebrain area (BFA) of freely moving cats during wakefulness (W), slow wave sleep (SWS) and paradoxical sleep (PS). Two classically synchronizing and hypnogenic regions, the preoptic area (POA) and the olfactory tubercle (OT) were explored by microelectrodes. Compared to W, the discharge rate in most of the POA cells was not modified or was slightly reduced by SWS, but it was increased by PS. Half of the OT cells increased slightly their firing frequency during falling asleep. A great proportion of OT neurones showed facilitation of activity during PS also, which in half of the cells started already in the last seconds of SWS. The results are discussed from the point of view of the synchronizing and hypnogenic influence attributed to POA and OT.

摘要

在自由活动的猫处于清醒(W)、慢波睡眠(SWS)和异相睡眠(PS)期间,对其基底前脑区(BFA)的神经元活动进行了研究。通过微电极探索了两个经典的同步化和促眠区域,即视前区(POA)和嗅结节(OT)。与清醒状态相比,大多数视前区细胞的放电率在慢波睡眠期间未发生改变或略有降低,但在异相睡眠期间增加。嗅结节的一半细胞在入睡过程中其放电频率略有增加。很大一部分嗅结节神经元在异相睡眠期间也表现出活动增强,其中一半细胞在慢波睡眠的最后几秒就已开始。从视前区和嗅结节的同步化和促眠影响的角度对结果进行了讨论。

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