Serratto M, Chawla K K, Miller R
G Ital Cardiol. 1984 Jun;14(6):387-94.
Treadmill exercise tests preformed on 13 patients with isolated congenital complete heart block are described. Premature ventricular contractions appeared with exercise in 5/13 patients. The 5 patients who developed ventricular ectopics with exercise had lesser increments in their junctional rates with exercise as compared to the remaining patients (P less than .025). Two of these 5 patients subsequently experienced syncope and required pacemaker insertion. The two groups of patients were indistinguishable in terms of age, sex, resting heart rates, presence or absence of cardiomegaly. The site of AV block appeared to be above the bundle of His in all instances (proven in 9/13). It is suggested that the association between ventricular ectopic activity and inadequate chronotropy with exercise could have a pathophysiological link and might indicate an unfavorable prognosis.
本文描述了对13例孤立性先天性完全性心脏传导阻滞患者进行的跑步机运动试验。13例患者中有5例在运动时出现室性早搏。与其余患者相比，这5例运动时出现室性异位心律的患者运动时交界区心率的增加幅度较小（P<0.025）。这5例患者中有2例随后出现晕厥，需要植入起搏器。两组患者在年龄、性别、静息心率、有无心脏扩大方面无差异。所有病例中房室传导阻滞部位似乎均在希氏束上方（13例中有9例得到证实）。提示运动时室性异位活动与变时性功能不全之间的关联可能存在病理生理联系，且可能预示预后不良。
