Masaki N, Nishiyama K, Ikeda H, Shigematsu Y, Fuchihata H, Tanaka Y
Gan No Rinsho. 1984 Aug;30(10):1231-4.
A clinical study comparing the use of radiation to the combination of bleomycin and radiation was carried out in 61 patients with carcinoma of the lower gum. For the 28 patients treated by radiation, the dose was 30-74 Gy, and, for the 33 treated by combination therapy, the dose of bleomycin was 45-120 mg and that of radiation was 20-52 Gy. The 5-year survival rate of the radiation-alone group was 0/12 (0%), and that of patients undergoing surgery after radiation was 7/16 (44%), whereas that of the combined bleomycin and radiation alone was 7/15 (47%) and that of surgery after combined treatment was 14/18 (78%).
对61例下牙龈癌患者进行了一项临床研究,比较了放射治疗与博来霉素联合放射治疗的效果。接受放射治疗的28例患者,剂量为30 - 74 Gy;接受联合治疗的33例患者,博来霉素剂量为45 - 120 mg,放射剂量为20 - 52 Gy。单纯放疗组的5年生存率为0/12(0%),放疗后接受手术的患者为7/16(44%),而博来霉素与放疗联合组为7/15(47%),联合治疗后接受手术的患者为14/18(78%)。