鸡胚神经视网膜在胚胎发育过程中对体外病毒增殖的易感性。
Susceptibility of chick neural retina to viral multiplication in vitro during embryonic development.
作者信息
Matsuno T, Shirasawa N, Umino Y, Katow S, Shishido A
出版信息
Experientia. 1978 Jan 15;34(1):54-5. doi: 10.1007/BF01921897.
PMID:620735
Abstract
Decrease in the susceptibility of embryonic chick neural retina cultures to the multiplication of various viruses was observed with increasing age of the embryo. In contrast the retinal cells supported the multiplication of Sindbis virus irrespective of the age when they were infected with the viral RNA. These results suggest that the restricted multiplication of the viruses observed is due to the modulated inability of the cell to process the adsorbed viruses for subsequent replication.
摘要
随着胚胎年龄的增加，观察到鸡胚神经视网膜培养物对各种病毒增殖的敏感性降低。相比之下，无论视网膜细胞在何时感染病毒RNA，它们都能支持辛德毕斯病毒的增殖。这些结果表明，观察到的病毒增殖受限是由于细胞处理吸附病毒以进行后续复制的能力受到调节性抑制。
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