合成Δ9-四氢大麻酚和大麻提取物对雄性大鼠类固醇代谢的不同影响。
Different effects of synthetic delta 9-tetrahydrocannabinol and cannabis extract on steroid metabolism in male rats.
作者信息
Maskarinec M P, Shipley G, Novotny M, Brown D J, Forney R B
出版信息
Experientia. 1978 Jan 15;34(1):88-9. doi: 10.1007/BF01921920.
PMID:620748
Abstract
Repeated oral administration of cannabis extract as well as synthetic delta9-tetrahydrocannabinol to male rats produced significant changes in excretion of androgenic steroids and their metabolites as detectable in blood and urine. Cannabis extracts were found to be significantly more active than the mixtures containing same amounts of synthetic cannabinoids.
摘要
对雄性大鼠反复口服大麻提取物以及合成的Δ9-四氢大麻酚，会导致雄激素类固醇及其代谢产物的排泄发生显著变化，这在血液和尿液中都可检测到。研究发现，大麻提取物的活性明显高于含有相同量合成大麻素的混合物。
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