Coronary vascular responsiveness to non-eicosanoid vasoconstrictors in the perfused diabetic rat heart.
作者信息
Roth D M, Foster K A, Lefer A M
出版信息
Res Commun Chem Pathol Pharmacol. 1984 Aug;45(2):317-20.
PMID:6207576
Abstract
We tested arginine vasopressin, and a dihydropyridine calcium agonist, BAY K-8644 in isolated perfused hearts from control and diabetic rats. Arginine vasopressin (1-100 ng/ml) and BAY K-8644 (100-500 ng/ml) significantly increased coronary perfusion pressure during constant flow perfusion indicative of coronary vasoconstriction. However, no significant potentiation was observed between diabetic rats and their weight matched controls for either vasoconstrictor.
摘要
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