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使用重组干扰素预防疱疹病毒复发排毒。

Use of recombinant interferon to prevent recurrent herpesvirus shedding.

作者信息

Smolin G, Matli M, Okumoto M, Mayers M, Samy M

出版信息

Curr Eye Res. 1984 Aug;3(8):1069-74. doi: 10.3109/02713688409011754.

Abstract

Iontophoresis with 6-hydroxydopamine was performed in rabbits previously infected with herpes simplex virus, McKrae strain. Viral shedding into the tear film was significantly decreased by the use of recombinant alpha interferon subtype D given as one drop qid. Interferon was noted in the tear film of rabbits 16-18 hours after the last placement of interferon drops into the inferior cul-de-sac.

摘要

对先前感染单纯疱疹病毒麦克雷株的家兔进行了6-羟基多巴胺离子导入。通过每天四次、每次一滴给予重组α干扰素D型,泪膜中的病毒脱落显著减少。在将干扰素滴眼液最后一次滴入下结膜穹窿16 - 18小时后,在家兔的泪膜中检测到了干扰素。

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