Gruer L D, Babb J R, Davies J G, Ayliffe G A, Adu D, Michael J
J Hosp Infect. 1984 Sep;5(3):305-12. doi: 10.1016/0195-6701(84)90080-x.
During a 3 month study the effectiveness of two methods of handwashing was assessed in a group of 31 patients undergoing continuous ambulatory peritoneal dialysis. A defined, double rinse with alcohol, prior to bag exchange, was found to be more convenient and significantly more effective than povidone-iodine alone or povidone-iodine followed by alcohol. Spraying the tubing around the bag connector with 70 per cent ethanol reduced the numbers of adherent skin organisms so reducing the likelihood of bacteria being drawn into the dialysate. Although there was no difference in the overall incidence of peritonitis in the two groups of patients studied, there was an unexpected drop in the incidence of peritonitis caused by coagulase-negative skin staphylococci. This was attributed to an overall awareness of the importance of handwashing and aseptic procedures during bag exchange. Monitoring the bacteriology of the catheter exit site may give some prior indication as to the likelihood of subsequent peritonitis especially with Staphylococcus aureus and Gram-negative bacilli.
在一项为期3个月的研究中，对31例接受持续性非卧床腹膜透析的患者评估了两种洗手方法的效果。结果发现，在更换透析袋之前使用规定的酒精进行两次冲洗，比单独使用聚维酮碘或先用聚维酮碘再用酒精更为方便且显著有效。用70%乙醇喷洒透析袋连接器周围的管路可减少皮肤黏附微生物的数量，从而降低细菌进入透析液的可能性。虽然在研究的两组患者中腹膜炎的总体发生率没有差异，但由凝固酶阴性皮肤葡萄球菌引起的腹膜炎发生率意外下降。这归因于在更换透析袋过程中对手部清洁和无菌操作重要性的全面认识。监测导管出口部位的细菌学情况可能会对后续发生腹膜炎的可能性给出一些预先提示，尤其是对于金黄色葡萄球菌和革兰氏阴性杆菌感染。
