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[P物质作为抵抗情绪应激的一个因素]

[Substance P as a factor in resistance to emotional stress].

作者信息

Iumatov E A, Gekht K, Skotselias Iu G

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Jul-Aug;34(4):771-7.

PMID:6208706
Abstract

The effect of substance P--an endogenous brain peptide--on the resistance to chronic emotional stress was studied in rats. A single administration of the peptide (125 or 250 mkg/kg) elicits a highly significant increase of rats resistance to chronic emotional stress and reduces the raise of adrenals weight, hemodynamic fluctuations and emotional reactivity.

摘要

研究了内源性脑肽P物质对大鼠慢性情绪应激抵抗力的影响。单次给予该肽(125或250微克/千克)可使大鼠对慢性情绪应激的抵抗力显著增强,并减少肾上腺重量增加、血流动力学波动和情绪反应性。

相似文献

1
[Substance P as a factor in resistance to emotional stress].[P物质作为抵抗情绪应激的一个因素]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Jul-Aug;34(4):771-7.
2
[The physiological properties of endogenous oligopeptides that enhance resistance to emotional stress].[增强对情绪应激抵抗力的内源性寡肽的生理特性]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 Mar-Apr;43(2):318-25.
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Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 May-Jun;41(3):558-63.
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[Changes in the substance P content of the blood and hypothalamus during experimental emotional stress].
Biull Eksp Biol Med. 1985 Apr;99(4):397-9.
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Zh Vyssh Nerv Deiat Im I P Pavlova. 1983 Jan-Feb;33(1):146-52.
7
Possible role of substance P on regulation of pituitary-adrenal axis.P物质在垂体-肾上腺轴调节中的可能作用。
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8
Prevention of stress-induced involution of the thymus in rats by substance P (SP1-11) and its N-terminal fragment SP1-4.
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[Effect of the N-terminal fragment of substance P1-4 on the somatic manifestations of the stress reaction and on the catecholamine content of the adrenals in rats].[P物质1-4的N端片段对大鼠应激反应躯体表现及肾上腺儿茶酚胺含量的影响]
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[Delta-sleep peptide as a factor increasing animal resistance to emotional stress].[作为增强动物对情绪应激抵抗力的一种因子的δ-睡眠肽]
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