Millar B W, Macdonald K J, Macleod T M, Raffle E J
Acta Derm Venereol. 1984;64(5):433-6.
Polymorphonuclear leucocyte chemotaxis was investigated in 6 patients with active dermatitis herpetiformis in the untreated state and when under control with Dapsone. Control studies were undertaken in 7 healthy volunteers. No significant difference in chemotaxis was demonstrated between the active, treated and control groups. Furthermore, when Dapsone in physiological concentrations was added separately in all three groups there was no additional effect on chemotaxis. These results clearly show that polymorphonuclear leucocytes from active untreated dermatitis herpetiformis have normal chemotactic activity compared with those from the same patients in the treated state and controls. Additional Dapsone did not alter these findings.
对6例未经治疗的活动性疱疹样皮炎患者以及使用氨苯砜病情得到控制时的趋化性进行了研究。对7名健康志愿者进行了对照研究。结果表明，活动组、治疗组和对照组之间在趋化性方面无显著差异。此外，在所有三组中分别添加生理浓度的氨苯砜后，对趋化性没有额外影响。这些结果清楚地表明，未经治疗的活动性疱疹样皮炎患者的多形核白细胞与处于治疗状态的同一患者及对照组相比，具有正常的趋化活性。额外添加氨苯砜并未改变这些结果。
