蛋白质周转的机制与调控：α-甘露糖苷酶抑制剂苦马豆素对糖蛋白降解的影响 - Suppr | 超能文献

Mechanism and regulation of protein turnover: effect of the alpha-mannosidase inhibitor, swainsonine, on glycoprotein degradation.

作者信息

Segal H L, Winkler J R

出版信息

Curr Top Cell Regul. 1984;24:229-49. doi: 10.1016/b978-0-12-152824-9.50029-0.

DOI:10.1016/b978-0-12-152824-9.50029-0

Abstract

摘要

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相似文献

1

Mechanism and regulation of protein turnover: effect of the alpha-mannosidase inhibitor, swainsonine, on glycoprotein degradation.蛋白质周转的机制与调控：α-甘露糖苷酶抑制剂苦马豆素对糖蛋白降解的影响

Curr Top Cell Regul. 1984;24:229-49. doi: 10.1016/b978-0-12-152824-9.50029-0.

2

Inhibition by swainsonine of the degradation of endocytosed glycoproteins in isolated rat liver parenchymal cells.苦马豆素对离体大鼠肝实质细胞内吞糖蛋白降解的抑制作用。

J Biol Chem. 1984 Feb 10;259(3):1958-62.

3

Swainsonine inhibits lysosomal degradation of glycoproteins.

Prog Clin Biol Res. 1985;180:491-4.

4

Use of active site-directed inhibitors to study in situ degradation of glycoproteins by the perfused rat liver.使用活性位点定向抑制剂研究灌注大鼠肝脏对糖蛋白的原位降解。

J Biol Chem. 1985 Feb 10;260(3):1858-66.

5

Swainsonine inhibits glycoprotein degradation by isolated rat liver lysosomes.

J Biol Chem. 1984 Dec 25;259(24):15369-72.

6

Substrate specificities of rat kidney lysosomal and cytosolic alpha-D-mannosidases and effects of swainsonine suggest a role of the cytosolic enzyme in glycoprotein catabolism.大鼠肾脏溶酶体和胞质α-D-甘露糖苷酶的底物特异性以及苦马豆素的作用表明胞质酶在糖蛋白分解代谢中发挥作用。

J Biol Chem. 1987 May 15;262(14):6506-14.

7

Swainsonine inhibits macrophage receptor-mediated uptake and degradation of a mannosyl-oligosaccharide.苦马豆素抑制巨噬细胞受体介导的甘露糖基寡糖的摄取和降解。

Biochem Biophys Res Commun. 1983 Nov 15;116(3):922-30. doi: 10.1016/s0006-291x(83)80230-7.

8

Swainsonine, a potent mannosidase inhibitor, elevates rat liver and brain lysosomal alpha-D-mannosidase, decreases Golgi alpha-D-mannosidase II, and increases the plasma levels of several acid hydrolases.苦马豆素是一种有效的甘露糖苷酶抑制剂，它能提高大鼠肝脏和脑溶酶体α-D-甘露糖苷酶的活性，降低高尔基体α-D-甘露糖苷酶II的活性，并提高几种酸性水解酶的血浆水平。

Arch Biochem Biophys. 1983 Jul 15;224(2):594-600. doi: 10.1016/0003-9861(83)90247-3.

9

The storage products in genetic and swainsonine-induced human mannosidosis.遗传性和苦马豆素诱导的人类甘露糖苷贮积症中的储存产物。

Biochem J. 1983 Dec 1;215(3):693-6. doi: 10.1042/bj2150693.

10

Marked differences in the swainsonine inhibition of rat liver lysosomal alpha-D-mannosidase, rat liver Golgi mannosidase II, and jack bean alpha-D-mannosidase.苦马豆素对大鼠肝脏溶酶体α-D-甘露糖苷酶、大鼠肝脏高尔基体甘露糖苷酶II和刀豆α-D-甘露糖苷酶的抑制作用存在显著差异。

Arch Biochem Biophys. 1985 Jan;236(1):427-34. doi: 10.1016/0003-9861(85)90643-5.

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