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[暴露于多氯农药的工人外周血白细胞中特定脱氢酶的细胞化学分析]

[Cytochemical analysis of selected dehydrogenases in peripheral blood leukocytes of workers exposed to polychlorinated pesticides].

作者信息

Hrycek A, Kalina Z, Owczarzy I

出版信息

Med Pr. 1984;35(3):185-9.

PMID:6209525
Abstract

In 36 workers occupationally exposed to polychlorinated pesticides (Gammexane, DDT) and in a control group, cytochemical investigations of lactate and succinate dehydrogenases (LDH and SDH, respectively) in peripheral blood leukocytes were performed. In comparison with the control group, in workers exposed to pesticides, reduction of colour intensity in neutrophiles for SDH and in lymphocytes both for SDH and LDH was observed. In discussion, an attempt was made to interpret the obtained investigation results which seem to indicate disturbances in pyruvate metabolism in peripheral blood lymphocytes.

摘要

对36名职业性接触多氯农药(六六六、滴滴涕)的工人以及一个对照组进行了外周血白细胞中乳酸脱氢酶和琥珀酸脱氢酶(分别为LDH和SDH)的细胞化学研究。与对照组相比,在接触农药的工人中,观察到嗜中性粒细胞中SDH的颜色强度降低,淋巴细胞中SDH和LDH的颜色强度均降低。在讨论中,试图对所获得的研究结果进行解释,这些结果似乎表明外周血淋巴细胞中丙酮酸代谢存在紊乱。

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