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Effect of antineoplastic drugs on fibroblast proliferation in rabbit aqueous humor.

作者信息

Kwong E M, Litin B S, Jones M A, Herschler J

出版信息

Ophthalmic Surg. 1984 Oct;15(10):847-51.

PMID:6209602
Abstract

An assay is described to test the ability of antineoplastic agents to slow fibroblast growth. The effect of bleomycin sulfate, cytosine arabinoside (cytarabine), and 5-fluorouracil on suppression of fibroblast proliferation in 20% rabbit aqueous humor was studied in vitro. All of the drugs exhibited some suppression of fibroblast proliferation at differing doses. The choice of target cell, however, was an important factor in the dose responses obtained.

摘要

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