实验性滤过性手术后房水的变化。

Aqueous humor changes after experimental filtering surgery.

作者信息

Radius R L, Herschler J, Claflin A, Fiorentino G

出版信息

Am J Ophthalmol. 1980 Feb;89(2):250-4. doi: 10.1016/0002-9394(80)90119-1.

Abstract

We studied aqueous humor of rhesus and owl monkeys for its effect on the growth of subconjunctival fibroblasts in tissue culture. Aqueous humor samples obtained before glaucoma surgery inhibited the initiation of growth of fibroblasts. However, postoperative aqueous humor samples supported growth of fibroblasts. The change in aqueous humor physiology lasted for up to two months after glaucoma surgery. Our study indicated that possibly material added to the postoperative aqueous humor inactivates an inhibitor normally present in primary aqueous humor. An alternative explanation would be that primary aqueous humor, in contrast to secondary aqueous humor, lacks sufficient nutrient material to support fibroblast growth in tissue culture.

摘要

我们研究了恒河猴和夜猴的房水对组织培养中结膜下成纤维细胞生长的影响。青光眼手术前获取的房水样本抑制了成纤维细胞生长的起始。然而，术后房水样本却支持成纤维细胞的生长。青光眼手术后房水生理变化持续长达两个月。我们的研究表明，可能是术后房水中添加的物质使原本存在于原发性房水中的一种抑制剂失活。另一种解释是，与继发性房水相比，原发性房水缺乏足够的营养物质来支持组织培养中成纤维细胞的生长。