[Effect of adrenalectomy and anti-adrenergic preparations on the development of hyperenzymic and biochemical changes in the blood in burns].

Activities of alpha-hydroxybutyrate- and lactate dehydrogenases (HBDH, LDH), aspartate- and alanine aminotransferases (AST, ALT), alkaline phosphatase, alpha-amylase as well as content of total proteins, glucose, cholesterol, triglycerides and Ca2+ were estimated sprectrophotometrically in blood serum of rat males within 2 hrs after thermic burns of the III degree involving 15% the body surface. The burns caused about 2-fold increase in activities of LDH, HBDH and AST and in content of triglycerides in blood serum but did not affect the other biochemical patterns. Adrenalectomy, carried out within 3 days before the burns, accelerated and pseudoadrenalectomy decreased the early postburn enzymatic activation. Preadministration of reserpine, phentolamine and obsidane (propranolol) decreased distinctly the hyperenzymic reaction observed after the burn stress.