Schermuly W, Sonnentag W
Rofo. 1982 Jan;136(1):49-55. doi: 10.1055/s-2008-1055994.
It is possible to evaluate the activity of sarcoidosis by means of 67 Ga scintigrams and radiographs. In known sarcoid with lung involvement, the scintigram can differentiate between the granulomatous and fibrous stage. The granuloma, which is reversible and requires treatment, must be distinguished from fibrosis, which causes permanent damage. In the early stages of treatment, the scintigram is more sensitive than the radiograph. When treatment is stopped, the scintigram is better than the radiograph in demonstrating the need for renewed therapy. Evidence of fibrosis on the radiograph, with increased activity on the scintigram, indicates the need for further treatment. 67Ga can also demonstrate enlarged hilar nodes and mediastinal nodes which are not visible on the radiograph.