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糖尿病母亲所生婴儿的淋巴细胞群体及对有丝分裂原的反应

Lymphocyte populations and responses to mitogens in infants of diabetic mothers.

作者信息

El Mohandes A, Touraine J L, Touraine F, Shukry A S, Salle B

出版信息

J Clin Lab Immunol. 1982 May;8(1):25-9.

PMID:6212685
Abstract

A group of 10 infants of diabetic mothers, born prematurely by Caesarian section was compared to an age-matched group of premature controls and to full-term newborns. There was no difference between the three groups in terms of lymphocyte populations at birth. The percentage of T-cells in the three groups was significantly lower than in adults but reached adult levels at 1 month of age. The mitogenic responses in infants of diabetic mothers was found significantly higher than in the two control groups at birth and remained so at one month of age. The suppressor T-cell activity was decreased in infants of diabetic mothers as compared with controls.

摘要

一组10名通过剖宫产早产的糖尿病母亲的婴儿与年龄匹配的早产对照组和足月新生儿进行了比较。三组在出生时的淋巴细胞群体方面没有差异。三组中T细胞的百分比显著低于成年人,但在1个月大时达到成人水平。发现糖尿病母亲的婴儿在出生时的促有丝分裂反应显著高于两个对照组,并且在1个月大时仍然如此。与对照组相比,糖尿病母亲的婴儿中抑制性T细胞活性降低。

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