Management of ectopic pregnancy is tailored to the clinical situation. Improved sensitivity of human chorionic gonadotropin radioimmunoassay and radioreceptor assay and the use of gray-scale ultrasonography allow early diagnosis. Laparoscopy increases the diagnostic yield prior to rupture. Management is as conservative as possible to preserve fertility, Rho(D) immune globulin prophylaxis is mandatory if the patient is Rh negative.