Heath D, Smith P, Jago R
J Pathol. 1982 Oct;138(2):115-27. doi: 10.1002/path.1711380203.
The histopathology of hyperplasia of the carotid bodies was studied in 6 cases of hypoxaemia and right ventricular hypertrophy secondary to pan-acinar emphysema, and in five cases of systemic hypertension with left ventricular hypertrophy. The features of the hyperplasia were the same in the two groups. There was proliferation of sustentacular (type II) cells and compression of central cores of chief (type I) cells. It is speculated that the hyperplasia of sustentacular cells is associated in some way with the prevention of retention of sodium ions and water which characterises hypoxic cor pulmonale in "blue bloaters", systemic hypertension, and ascent to high altitude with the complications of acute mountain sickness, and pulmonary and cerebral oedema.
对6例继发于全腺泡型肺气肿的低氧血症和右心室肥厚患者，以及5例系统性高血压伴左心室肥厚患者的颈动脉体增生的组织病理学进行了研究。两组增生的特征相同。存在支持细胞（II型细胞）增殖以及主细胞（I型细胞）中央核心受压的情况。据推测，支持细胞的增生在某种程度上与预防“蓝肿型”慢性肺源性心脏病、系统性高血压、高原上升伴急性高原病并发症以及肺水肿和脑水肿中所特有的钠离子和水潴留有关。
