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小鼠肾细胞癌:一种合适的人类模型。

Murine renal cell carcinoma: a suitable human model.

作者信息

Murphy G P

出版信息

Prog Clin Biol Res. 1982;100:175-206.

PMID:6216486
Abstract

Many models of renal cell carcinoma are available. They have been observed in various species of animals. However, a renal adenocarcinoma which metastasizes, is available for study, and can be serially transplanted in BALB/c mice, appears to be the currently favored model. Our results reported herein describe a study on tumor kinetics, the effects of chemotherapy and other manipulations which appear relevant to the human state. A brief description of other available models is provided.

摘要

有许多肾细胞癌模型可供使用。它们已在各种动物物种中被观察到。然而,一种可转移的肾腺癌,可供研究且能在BALB/c小鼠中连续传代移植,似乎是目前最受青睐的模型。我们在此报告的结果描述了一项关于肿瘤动力学、化疗及其他与人类情况相关操作的影响的研究。还提供了其他可用模型的简要描述。

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