Fassbinder W, Frei U, Schoeppe W, Dathe G, Jonas D, Knöner M, Weber W
Urologe A. 1982 Sep;21(5):290-5.
Between 1973 and 1981 23 transplantations of kidneys from living related donors have been performed in Frankfurt/Main. Donor complications were haematopneumothorax (1 case) and reversible urinary tract infections (3 cases). All donors were discharged after 8-12 days, all have until now (6 months to 8 years postoperatively) normal excretory renal function and normal arterial blood pressure. Patient-survival in the recipients is 5 years postoperatively 96% and graft-survival is 90%. Nine patients received HLA-identical kidneys, all have excellent to fair function of the grafts, 7 patients are off steroids. In 14 cases kidneys were transplanted, although donor and recipient shared only one haplotype. In these patients 5-year graft survival is 84%. Seven patients have normal graft function, whereas 6 patients have a reduced function or have rejected. One patient died. Results of kidney transplantation using living related donors are--even when donors with only one haplotype-identity are accepted--much better than those obtainable when using cadaveric donors. When renal transplantation is considered, patients should be informed about the favourable results attainable with kidneys from living related donors.
1973年至1981年间，在美因河畔法兰克福共进行了23例亲属活体供肾移植手术。供者并发症包括血气胸（1例）和可逆性尿路感染（3例）。所有供者均在术后8 - 12天出院，截至目前（术后6个月至8年），其肾功能排泄及动脉血压均正常。受者术后5年的生存率为96%，移植肾生存率为90%。9例患者接受了HLA配型相同的肾脏，所有移植肾的功能均良好至尚可，7例患者已停用类固醇药物。14例患者接受的移植肾供者与受者仅共享一个单倍型。这些患者的移植肾5年生存率为84%。7例患者移植肾功能正常，而6例患者的移植肾功能减退或发生了排斥反应。1例患者死亡。亲属活体供肾移植的结果——即使接受供者与受者仅共享一个单倍型的情况——也远优于尸体供肾移植的结果。在考虑进行肾移植时，应告知患者亲属活体供肾可取得良好的效果。
