癌患者厌氧感染的羟羧氧酰胺菌素治疗
Moxalactam treatment of anaerobic infections in cancer patients.
作者信息
Lagast H, Meunier-Carpentier F, Klastersky J
出版信息
Antimicrob Agents Chemother. 1982 Oct;22(4):604-10. doi: 10.1128/AAC.22.4.604.
Abstract
Of 30 patients with predominantly anaerobic localized infections superimposed on chronic tissue damage related to trauma, ischemia, or tumor, 22 (73%) responded satisfactorily to moxalactam therapy. Moxalactam-resistant anaerobic pathogens emerged in two patients and were responsible for treatment failure. In six patients, two of whom also acquired resistant anaerobic pathogens, isolation of moxalactam-resistant aerobic pathogens increased during therapy.
摘要
在30例主要为厌氧性局部感染叠加于与创伤、缺血或肿瘤相关的慢性组织损伤的患者中，22例（73%）对拉氧头孢治疗反应良好。2例患者出现了对拉氧头孢耐药的厌氧性病原体，导致治疗失败。在6例患者中，其中2例也获得了耐药厌氧性病原体，治疗期间对拉氧头孢耐药的需氧病原体分离率增加。
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