[Detection of collagen by immunofluorescence during development of Xenopus (Xenopus laevis Daud.)].

Appearance of the different collagen types was studied during the clawed toad development from hatching to metamorphosis, using indirect immunofluorescence techniques. Type-like IV collagen of basement membranes was first seen in the notochord streath. Type I, type II were detected at the same time, followed by type III. Developmental sequence and distribution of the four collagen types indicate the different stages of organogenesis.