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乳腺癌转移所致腋窝淋巴结的组织酶学及超微结构变化

Histoenzymological and ultrastructural changes of axillary lymph nodes with breast cancer metastases.

作者信息

Bârsu M, Cotuţiu G, Dobrescu G, Carasevici E, Stoica L

出版信息

Morphol Embryol (Bucur). 1982 Oct-Dec;28(4):299-302.

PMID:6218399
Abstract

Histoenzymatic and ultrastructural changes were studied in axillary lymph nodes from patients with breast cancer by comparison between lymph nodes without metastases, with incipient metastases and completely metastatically transformed. Metastases is preceded by intense macrophagic reactions of lymph nodes, and prepared by the development of vascular stroma. Neoplastic cells in course of invasion presented an intense respiratory activity, while those replacing the lymphoid elements an accentuated synthesis of glycoproteins.

摘要

通过对无转移、有早期转移和完全转移转化的乳腺癌患者腋窝淋巴结进行比较,研究了其组织酶学和超微结构变化。转移之前淋巴结会出现强烈的巨噬细胞反应,并由血管基质的发育所促成。侵袭过程中的肿瘤细胞呈现出强烈的呼吸活性,而取代淋巴样成分的肿瘤细胞则表现出糖蛋白合成增强。

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