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Flushing in rosacea: a possible mechanism.

作者信息

Guarrera M, Parodi A, Cipriani C, Divano C, Rebora A

出版信息

Arch Dermatol Res. 1982;272(3-4):311-6. doi: 10.1007/BF00509061.

DOI:10.1007/BF00509061
PMID:6219630
Abstract

Flushing in rosacea has been investigated by means of (a) pharmacological inhibition of some possible chemical mediators and (b) titration of bradykinin as a possible effector directly in the blood. Clonidine-inhibited flushing was seen in all patients (mean 45%), other drugs had poorer results. Bradykinin increased in all patients at the climax of flushing (mean 60%). These findings support the hypothesis that epinephrine promotes a bradykinin release responsible for vasodilation.

摘要

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1
Flushing in rosacea: a possible mechanism.
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The Risk of Rosacea According to Chronic Diseases and Medications: A 5-Year Retrospective, Multi-Institutional Case-Control Study.根据慢性病和药物治疗情况分析酒渣鼻的风险：一项为期5年的回顾性、多机构病例对照研究。
Ann Dermatol. 2018 Dec;30(6):676-687. doi: 10.5021/ad.2018.30.6.676. Epub 2018 Oct 26.
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Alcohol intake and risk of rosacea in US women.

本文引用的文献

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Observations on the effects of infusion of prostaglandin E in man.关于前列腺素E输注对人体影响的观察
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Flushing in rosacea: an experimental approach.酒渣鼻的潮红：一种实验方法。
Arch Dermatol Res. 1980;269(3):269-73. doi: 10.1007/BF00406420.
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Recent developments in noradrenergic neurotransmission and its relevance to the mechanism of action of certain antihypertensive agents.去甲肾上腺素能神经传递的最新进展及其与某些抗高血压药物作用机制的相关性。
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