Stavem P, Førre O, Brandtzaeg P, Nyberg H
Scand J Haematol. 1983 Feb;30(2):177-82. doi: 10.1111/j.1600-0609.1983.tb01467.x.
A 62-year-old Norwegian male was found to have a leucocytosis (20 X 10(9)/l blood). About 80% of the leucocytes were T-lymphocytes with markedly convoluted, often cerebriforme nuclei. There were generalized pea-sized lymph nodes. The liver was enlarged and was found to be infiltrated with the same type of lymphocytes as were found in the blood. A bone marrow biopsy showed massive infiltration with the same kind of cells. The patient had a non-specific rash, but no generalized exfoliative dermatitis. A double set of markers was found on the T-lymphocytes, with a membrane phenotype T4+ and T8+ on practically all cells.
一名62岁的挪威男性被发现白细胞增多（血液中白细胞计数为20×10⁹/L）。约80%的白细胞为T淋巴细胞，其核明显卷曲，常呈脑回状。全身有豌豆大小的淋巴结。肝脏肿大，发现有与血液中相同类型的淋巴细胞浸润。骨髓活检显示有大量同类细胞浸润。患者有非特异性皮疹，但无全身性剥脱性皮炎。在T淋巴细胞上发现了两组标志物，几乎所有细胞的膜表型均为T4⁺和T8⁺。
