Salmon C, Delerue-Le Belle N, Fontaine Y A
C R Seances Soc Biol Fil. 1982;176(6):787-94.
Carp gonadotropin (cGTH) stimulated adenylate cyclase from 20-24 day old (but not 16-18 day old) rat ovaries; its subunits were inactive. Carp GTH (but not its subunits) increased the apparent KD for oFSH but not for oLH. These results suggest that cGTH mainly interacts with FSH sensitive adenylate cyclase-receptor systems, with an efficiency about 6 X 10(3) times lower than oFSH itself.
鲤鱼促性腺激素(cGTH)刺激20 - 24日龄(而非16 - 18日龄)大鼠卵巢的腺苷酸环化酶;其亚基无活性。鲤鱼促性腺激素(而非其亚基)增加了对大鼠促卵泡激素(oFSH)而非大鼠促黄体生成素(oLH)的表观解离常数(KD)。这些结果表明,鲤鱼促性腺激素主要与促卵泡激素敏感的腺苷酸环化酶 - 受体系统相互作用,其效率比大鼠促卵泡激素本身低约6×10³倍。