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[消化脏器的电生理活动与从腹壁接收的信号之间的关系。清醒大鼠的初步结果]

[Relation between the electrophysiological activities of the digestive viscera and the signals received from the abdominal wall. Initial results in the waking rat].

作者信息

Santini R, Boiron M, Thouvenot J

出版信息

Pathol Biol (Paris). 1983 Jan;31(1):28-32.

PMID:6222279
Abstract

Experiments in the unanesthetized rats were made to examine the possibilities of relations between visceral and abdominal sites of electrodes implantation. From gastric duodenal ileal electrodes wire, relations may be observed with the surface records with the following limitation: in the frequencies greater than or equal to 200 cycles/mn ("A" range) the spiking visceral activity is never found from surface derivation where the EKG is frequently present. In the ranging of 60 to 80 cycles/mn correspondences of the signals are in relation with respiratory transmission. The slower frequencies from surface activity (longlasting RC time constant of 6 s are used) concern duodenal (38,8 +/- 0,98 cycles/mn) and ileal (28,6 +/- 1,9 cycles/mn) slow waves activities may be recognized in the sequences during several minutes in alternation with the C type activities. In such conditions of typical correspondences, it may be noticed modifications of signal during the viscero-parietal transmission: attenuation (averaging 0,7); dephasage of 5 to 12 seconds (swing to strong capacitive component acting as an active filter) and mixing with others activities not be identified. The methodological interest for a non invasive characterization of visceral physiological states is discussed.

摘要

在未麻醉的大鼠身上进行了实验,以研究电极植入的内脏部位与腹部部位之间关系的可能性。从胃、十二指肠、回肠电极导线可以观察到与体表记录的关系,但有以下限制:在频率大于或等于200次/分钟(“A”范围)时,从经常出现心电图的体表导联中从未发现尖峰状内脏活动。在60至80次/分钟的范围内,信号的对应关系与呼吸传导有关。体表活动较慢的频率(使用持续时间长的6秒RC时间常数)涉及十二指肠(38.8±0.98次/分钟)和回肠(28.6±1.9次/分钟)的慢波活动,在几分钟内可与C型活动交替出现的序列中识别出来。在这种典型对应关系的情况下,可以注意到内脏-壁层传导过程中信号的变化:衰减(平均0.7);5至12秒的相位差(转向作为有源滤波器的强电容性成分)以及与其他无法识别的活动混合。讨论了对内脏生理状态进行非侵入性表征的方法学意义。

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