Kop'eva T N, Vladimirov V V
Arkh Patol. 1983;45(3):89-94.
Data from the literature on morphological features of foci of lesions on the skin which is the main target of the pathological process in psoriasis are presented as well as the materials confirming the systemic nature of the disease. The important role of immunopathological responses in the pathogenesis of psoriasis is emphasized. Viruses, congenital defects in the immune regulatory system, cellular membranes of the epidermis, blood and lymph vessels are discussed as possible etiological factors. The morphology of regression of psoriatic foci of lesions under the influence of photochemotherapy is described.
本文呈现了文献中关于银屑病病理过程主要靶点——皮肤病变病灶形态学特征的数据,以及证实该疾病全身性的资料。强调了免疫病理反应在银屑病发病机制中的重要作用。探讨了病毒、免疫调节系统的先天性缺陷、表皮、血液和淋巴管的细胞膜作为可能的病因。描述了光化学疗法影响下银屑病病灶消退的形态。