Seiga K, Sugiyama Y, Yamaji K
Jpn J Antibiot. 1982 Oct;35(10):2354-63.
We studied piperacillin (PIPC) clinically to evaluate its utility and safety, and obtained the following results. PIPC was given at a daily dose of 1 approximately 4 g for 3 approximately 10 days by bolus injection or dripping infusion to 18 patients with various infections in the field of obstetrics and gynecology. Four of 5 cases with intrauterine infection, 2 of 3 cases with focus infection of uterine cancer, 2 cases with perinatal intrauterine infection, 2 of 6 cases with adnexal infection and 2 cases with vulvar infection proved to respond effectively. The overall efficacy rate was 66.7%. No side effect or abnormal laboratory findings were observed except for 1 case with rash.
我们对哌拉西林(PIPC)进行了临床研究以评估其效用和安全性,结果如下。对18例妇产科各种感染患者,通过静脉推注或滴注给予PIPC,每日剂量约1至4g,疗程3至10天。5例子宫内感染患者中有4例、3例子宫癌病灶感染患者中有2例、2例围产期子宫内感染患者、6例附件感染患者中有2例以及2例外阴感染患者被证明有效。总有效率为66.7%。除1例出现皮疹外,未观察到副作用或实验室检查异常结果。