急性心肌梗死的冠状动脉内溶栓治疗。
Intracoronary thrombolysis in acute myocardial infarction.
作者信息
Ganz W
出版信息
Am J Cardiol. 1983 Jul 20;52(2):92A-95A. doi: 10.1016/0002-9149(83)90182-0.
Forty-seven patients with acute myocardial infarction (MI) underwent intracoronary infusion of Thrombolysin or streptokinase. In 41, a completely reoccluded artery was reopened. Patency was associated with appearance of arrhythmias, relief of pain, gradual return of the ST-segment to the baseline and appearance of abnormal Q waves. Creatine kinase (CK) and MB-CK enzyme levels peaked earlier. Serial thallium scintigrams showed reduction in defect size after reperfusion, and the ejection fraction was higher compared with control. Eighteen patients were recommended for coronary bypass surgery for recurrent pain or severe multivessel disease.
47例急性心肌梗死（MI）患者接受了冠状动脉内注射溶栓酶或链激酶治疗。其中41例患者闭塞的动脉完全再通。血管再通与心律失常的出现、疼痛缓解、ST段逐渐恢复至基线以及异常Q波的出现有关。肌酸激酶（CK）和肌酸激酶同工酶（MB-CK）水平峰值出现得更早。系列铊闪烁扫描显示再灌注后缺损面积减小，与对照组相比射血分数更高。18例患者因复发性疼痛或严重多支血管病变被建议接受冠状动脉搭桥手术。
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