免疫规划后对麻疹活病毒疫苗的严重局部反应。
Severe local reactions to live measles virus vaccine following an immunization program.
作者信息
Stetler H C, Gens R D, Seastrom G R
出版信息
Am J Public Health. 1983 Aug;73(8):899-900. doi: 10.2105/ajph.73.8.899.
A cluster of nine severe local reactions occurred in a Pennsylvania school district following a mass measles immunization program in February 1981. A case-control study showed that the nine cases had a statistically significant increased history of having received killed measles vaccine previously (p less than .001, Fisher's exact test) and a statistically significant higher geometric mean measles antibody titer (p less than .01, Student's t test) than controls, suggesting that previous receipt of killed measles vaccine was the underlying cause of these reactions.
1981年2月，宾夕法尼亚州一个学区在开展大规模麻疹免疫计划后，出现了9例严重局部反应的聚集性病例。一项病例对照研究表明，与对照组相比，这9例病例既往接种过麻疹灭活疫苗的历史在统计学上有显著增加（P<0.001，Fisher精确检验），且麻疹抗体几何平均滴度在统计学上显著更高（P<0.01，Student t检验），这表明既往接种麻疹灭活疫苗是这些反应的根本原因。
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