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[二维应力超声心动图和血浆儿茶酚胺测量在生理性肥厚心脏评估中的应用]

[Two-dimensional stress echocardiography and plasma catecholamine measurements in the evaluation of the physiologically hypertrophied heart].

作者信息

Dickhuth H H, Lehmann M, Abel R, Keul J

出版信息

Z Kardiol. 1983 May;72(5):268-76.

PMID:6224355
Abstract

Two-dimensional stress echocardiography was performed in 8 untrained subjects, 8 long-distance runners, and 8 cyclists. The ergometric investigation was performed with subjects in supine position on a bicycle ergometer with increasing work loads of 50 Watts. At each working level, lactate, norepinephrine, and epinephrine were measured. The long-distance runners and the cyclists had an equal maximum oxygen uptake when tested with treadmill or bicycle ergometer. Absolute and relative heart volumes also showed the same amount of hypertrophy. In spite of this, lactate, catecholamines, and heart rate of the long-distance runners rose earlier during the supine ergometer test. End-diastolic volume and stroke volume in the cyclists increased significantly more (delta EDV = 15%, delta SV = 32%) than in the long-distance runners (delta EDV = 1%, delta SV = 13%) and untrained subjects (delta EDV = 5%, delta SV = 9%). It is assumed that this difference in heart function is caused by diminished sympathetic activity, which is dependent on the aerobic capacity of the working muscles.

摘要

对8名未经训练的受试者、8名长跑运动员和8名自行车运动员进行了二维应力超声心动图检查。在自行车测力计上对处于仰卧位的受试者进行测力研究,工作负荷以50瓦递增。在每个工作水平,测量乳酸、去甲肾上腺素和肾上腺素。当用跑步机或自行车测力计测试时,长跑运动员和自行车运动员的最大摄氧量相等。绝对和相对心脏容积也显示出相同程度的肥大。尽管如此,在仰卧测力计测试期间,长跑运动员的乳酸、儿茶酚胺和心率上升得更早。自行车运动员的舒张末期容积和每搏输出量增加幅度(舒张末期容积增量=15%,每搏输出量增量=32%)明显大于长跑运动员(舒张末期容积增量=1%,每搏输出量增量=13%)和未经训练的受试者(舒张末期容积增量=5%,每搏输出量增量=9%)。据推测,这种心脏功能差异是由交感神经活动减弱引起的,而交感神经活动减弱取决于工作肌肉的有氧能力。

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