Hyde D, Scott J J
J Neurophysiol. 1983 Aug;50(2):344-57. doi: 10.1152/jn.1983.50.2.344.
The responses of regenerated muscle spindle afferents to ramp-and-hold stretch of the peroneus brevis muscle in the cat were recorded at periods from 26 to 140 days after crushing the common peroneal nerve. During the early stages of recovery a number of abnormally responding afferents were observed. The most marked abnormality was the absence or rapid failure of firing during the held phase of the stretch. The proportion of abnormal afferents became less as recovery progressed. Electrical stimulation of isolated static and dynamic gamma-axons increased the firing rates of the afferents during the ramp-and-hold stretch such that a gamma static axon would restore the response of an abnormal afferent to the held phase of the stretch. The regenerated afferents have been classified according to the degree of abnormality displayed. These abnormalities can be accounted for by assuming a subtractive reduction in the firing frequency of the regenerated afferents. This is attributed to an increase in the pacemaker threshold.
在猫的腓总神经被挤压后的26至140天期间，记录了再生肌梭传入纤维对腓骨短肌斜坡-保持拉伸的反应。在恢复的早期阶段，观察到一些反应异常的传入纤维。最明显的异常是在拉伸的保持阶段放电缺失或迅速停止。随着恢复进程的推进，异常传入纤维的比例逐渐减少。对分离的静态和动态γ轴突进行电刺激，可在斜坡-保持拉伸期间提高传入纤维的放电率，从而使γ静态轴突能恢复异常传入纤维对拉伸保持阶段的反应。已根据所表现出的异常程度对再生传入纤维进行了分类。这些异常可以通过假设再生传入纤维放电频率的减法性降低来解释。这归因于起搏器阈值的增加。
