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腹裂:新生儿特征与躯体发育

Gastroschisis: neonatal features and somatic development.

作者信息

Kekomäki M, Savilahti E, Louhimo I

出版信息

J Pediatr Gastroenterol Nutr. 1982;1(3):369-73.

PMID:6224923
Abstract

Thirty-nine newborns were treated for gastroschisis at the Children's Hospital, Helsinki University Central Hospital from 1964 to 1980. Sixteen infants died during the first hospital admission. Of the 23 survivors, 11 were two years or older, and these 11 children were subjected to a follow-up examination. The incidence of the lesion increased markedly during the period of observation. Dysmaturity (birth weight at or below the 10th percentile of normal intrauterine growth) accompanied gastroschisis in 17 cases, and a low birth weight (below 2,500 g) in 23 cases. The mortality of gastroschisis was clearly and constantly decreasing, being 54% for the first decade, 23% for the last 5 years, and 41% for the total series. The age of the mothers at parturition, 20.9 years, was significantly (p less than 0.001) lower than the Finnish average. The extensive clinical and laboratory analysis of the 11 oldest children with completed reconstruction of the abdominal wall indicated good physical condition and, specifically, normal absorptive function of the intestine.

摘要

1964年至1980年期间,赫尔辛基大学中心医院儿童医院对39例腹裂新生儿进行了治疗。16例婴儿在首次住院期间死亡。在23名幸存者中,11名年龄在两岁或以上,这11名儿童接受了随访检查。在观察期内,该病变的发病率显著增加。17例腹裂患儿伴有发育不成熟(出生体重处于或低于正常宫内生长第10百分位数),23例出生体重低(低于2500克)。腹裂的死亡率明显且持续下降,第一个十年为54%,最后五年为23%,整个系列为41%。分娩时母亲的年龄为20.9岁,显著低于芬兰平均水平(p<0.001)。对11名腹壁重建完成的年龄最大的儿童进行的广泛临床和实验室分析表明,他们身体状况良好,特别是肠道吸收功能正常。

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