Berseth C L, Malachowski N, Cohn R B, Sunshine P
J Pediatr Gastroenterol Nutr. 1982;1(3):375-9. doi: 10.1097/00005176-198201030-00017.
Of 22 survivors of gastroschisis and omphalocele, most had poor weight gain. Although one-third of gastroschisis babies were small-for-gestational age at birth, no other predisposing factors for poor growth could be demonstrated. No child had intrinsic gastrointestinal or metabolic sequelae at 3 years of age, as demonstrated by radiographic studies, fecal fat excretion, or serum chemistry screen. One-third of those tested had IQs less than 90; five had abnormal electroencephalograms; one had impaired hearing. Intellectual impairment was related to length of hospitalization due to a variety of nongastrointestinal factors. Neither growth nor intellectual development was related to the type of lesion present, even when IQ is corrected for prematurity. Impairment of growth and intellectual outcome may be related to prematurity, small-for-gestation birth weight, and nongastrointestinal neonatal complications.
在22名腹裂和脐膨出幸存者中，大多数体重增加不佳。虽然三分之一的腹裂患儿出生时为小于胎龄儿，但未发现其他导致生长不良的易感因素。3岁时，通过影像学检查、粪便脂肪排泄或血清化学筛查，未发现患儿有内在的胃肠道或代谢后遗症。三分之一接受测试的儿童智商低于90；5名儿童脑电图异常；1名儿童听力受损。智力障碍与因各种非胃肠道因素导致的住院时间长短有关。即使对早产进行了智商校正，生长和智力发育均与所患病变类型无关。生长发育受损和智力结局可能与早产、小于胎龄出生体重以及非胃肠道新生儿并发症有关。
