Lopez-Majano V, Renzi G
Respiration. 1978;35(1):53-63. doi: 10.1159/000193859.
Pulmonary function testing is needed to determine the pathophysiology present in the patient with cardiopulmonary disease. Blood gases and pH should be obtained during emergency situations and during cranial, thoracic, and extensive cervical or abdominal surgery. Lung function tests can be divided in global such as spirometry and diffusing capacity which study the ventilation and transfer of gases and regional determinations of ventilation and perfusion. Both types of tests complement each other and should be used together. The spirometry should consist at least of determination of the vital capacity and is determined in the first second to ascertain if there is obstructive lung disease. Some tests such as flow-volume curves, alveolar-arterial gradients and closing volume are very useful to detect early pulmonary disease before any symptoms or findings are present. This is probably one of the most important medical indications for pulmonary function testing. Before certain types of surgery pulmonary function testing is indicated; if the spirometry and diffusing capacity tests are normal, there is no pulmonary contraindication for the planned surgery. In chest surgery if there is significant compromise of the spirometry and diffusing capacity regional lung function tests are indicated to study the pathophysiology at regional level, thus trying to circumscribe the lung resection to the diseased areas.
需要进行肺功能测试以确定心肺疾病患者存在的病理生理学情况。在紧急情况下以及颅脑、胸部和广泛的颈部或腹部手术期间,应获取血气和pH值。肺功能测试可分为整体测试,如肺活量测定和弥散功能测定,用于研究气体的通气和转运,以及通气和灌注的区域测定。这两种测试相互补充,应一起使用。肺活量测定至少应包括肺活量的测定,并在第一秒内进行测定,以确定是否存在阻塞性肺病。一些测试,如流量-容积曲线、肺泡-动脉氧分压差和闭合容积,对于在出现任何症状或体征之前检测早期肺部疾病非常有用。这可能是肺功能测试最重要的医学指征之一。在某些类型的手术前需要进行肺功能测试;如果肺活量测定和弥散功能测试正常,则计划进行的手术没有肺部禁忌证。在胸部手术中,如果肺活量测定和弥散功能有显著损害,则需要进行区域肺功能测试,以研究区域水平的病理生理学,从而尽量将肺切除术局限于病变区域。