Hollman J, Gruentzig A R, Douglas J S, King S B, Ischinger T, Meier B
Circulation. 1983 Oct;68(4):725-32. doi: 10.1161/01.cir.68.4.725.
Between July 1980 and November 1982, there were 935 coronary angioplasties attempted at Emory University Hospital. Of these patients, 20 developed acute occlusion. Of these 20, 19 presented within 3 hr of surgery or within 3 hr after stopping a continuous heparin infusion. Five patients required emergency surgery, but in 15 nitrates, nifedipine, and/or repeat angioplasty reopened the artery and the patient could be stabilized on continuous infusions of heparin and nitroglycerin. In only one case was an occluding thrombus evident on angiographic examination. The mechanism of acute occlusion is unknown, but coronary artery spasm may play a role.
1980年7月至1982年11月期间，埃默里大学医院共尝试了935例冠状动脉血管成形术。在这些患者中，有20例发生了急性闭塞。在这20例中，19例在手术3小时内或停止持续肝素输注后3小时内出现。5例患者需要紧急手术，但15例患者通过使用硝酸盐、硝苯地平及/或再次进行血管成形术使动脉重新开通，患者在持续输注肝素和硝酸甘油后病情得以稳定。血管造影检查仅在1例中发现有闭塞性血栓。急性闭塞的机制尚不清楚，但冠状动脉痉挛可能起了一定作用。
