Meier B, Gruentzig A R, Siegenthaler W E, Schlumpf M
Circulation. 1983 Oct;68(4):796-802. doi: 10.1161/01.cir.68.4.796.
In our first 169 consecutive patients admitted to undergo percutaneous transluminal coronary angioplasty (PTCA) serial bicycle ergometric exercise sessions were scheduled to assess long-term-exercise performance. In 160 of these 169 patients (95%) an average of seven ergometric measurements were available during a mean follow-up period of 29 months (range 1 to 60 months). Two groups were formed. One consisted of 132 patients in whom PTCA was successful and the other consisted of 28 patients with failure of PTCA who subsequently underwent coronary artery bypass grafting (CABG) either on an emergency basis (12 patients) or as an elective procedure (16 patients). Exercise performance was expressed as work capacity in watts according to the highest completed exercise stage. In the successful PTCA group the actual work capacities increased from 74 +/- 42 W (mean +/- SD) before PTCA to 122 +/- 47 W at the most recent follow-up examination. In patients who underwent emergency or elective CABG the respective figures were 73 +/- 34 or 65 +/- 37 W before surgery and 120 +/- 41 or 119 +/- 41 W at the most recent follow-up examination (p less than .005 for all preprocedure to postprocedure comparisons). Successful PTCA and CABG after failed PTCA improve work capacity significantly. Comparison of our results with those of surgical studies indicates that a failed attempt at PTCA before CABG does not compromise the functional outcome of the operation, regardless whether it is done on an emergency or on an elective basis.
在我们首批连续收治的169例接受经皮腔内冠状动脉成形术(PTCA)的患者中,安排了系列踏车测力计运动试验以评估长期运动表现。在这169例患者中的160例(95%),在平均29个月(范围1至60个月)的随访期内平均有七次测力计测量数据。分为两组。一组由132例PTCA成功的患者组成,另一组由28例PTCA失败的患者组成,这些患者随后接受了冠状动脉旁路移植术(CABG),其中12例为急诊手术,16例为择期手术。运动表现根据完成的最高运动阶段以瓦特为单位的工作能力来表示。在PTCA成功组中,实际工作能力从PTCA前的74±42瓦(均值±标准差)增加到最近一次随访检查时的122±47瓦。在接受急诊或择期CABG的患者中,术前相应的数据分别为73±34瓦或65±37瓦,最近一次随访检查时为120±41瓦或119±41瓦(所有术前与术后比较,p<0.005)。成功的PTCA以及PTCA失败后行CABG均能显著提高工作能力。将我们的结果与外科研究结果进行比较表明,CABG前行PTCA的失败尝试并不会影响手术的功能结局,无论手术是急诊还是择期进行。