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扁平苔藓中单核细胞的原位鉴定。

In situ identification of mononuclear cells in lichen planus.

作者信息

Tosca A, Varelzidis A, Michalopoulos M, Georgala S, Stratigos J

出版信息

Dermatologica. 1983;167(3):113-20. doi: 10.1159/000249763.

Abstract

In this study, the in situ immunological typing of cell populations in lichen planus was attempted. T lymphocytes and suppressor/cytotoxic subsets, B lymphocytes, macrophages, immunocytes and Langerhans' cells were studied by one or more technical parameters and semiquantitative assessment of T cell populations were carried out. A critical evaluation of assays for T cell characterization was also attempted. T cells were found predominant in lichen planus infiltrate but macrophages were also many. Langerhans' cells were increased in the epidermis compared to normal skin and contact dermatitis.

摘要

在本研究中,尝试了扁平苔藓中细胞群体的原位免疫分型。通过一种或多种技术参数对T淋巴细胞及其抑制/细胞毒性亚群、B淋巴细胞、巨噬细胞、免疫细胞和朗格汉斯细胞进行了研究,并对T细胞群体进行了半定量评估。还尝试对T细胞特征分析方法进行批判性评价。发现T细胞在扁平苔藓浸润中占主导地位,但巨噬细胞数量也很多。与正常皮肤和接触性皮炎相比,表皮中的朗格汉斯细胞有所增加。

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