Toussaint D, Périer O, Verstappen A, Bervoets S
J Clin Neuroophthalmol. 1983 Sep;3(3):211-20.
The pathological study of the cerebral hemispheres and visual pathways in 32 cases of disseminated sclerosis, including 15 cases in which the retinal structures were investigated, lead us to point out: 1) the high frequency of histological lesions of the optic nerves, tracts and radiations; 2) the lack of correlation between the extent of demyelination of the optic nerves and the impairment of visual acuity that is mainly related to axonal lesions; 3) the relative high frequency of pathological sheathing of retinal veins; and 4) the high proportion of shadow plaques in the cerebral hemispheres in cases with clear-cut relapses and remissions.
对32例播散性硬化患者的大脑半球和视觉通路进行病理研究，其中15例还对视网膜结构进行了研究，这使我们指出：1）视神经、视束和视放射组织学病变的高发生率；2）视神经脱髓鞘程度与主要与轴突病变相关的视力损害之间缺乏相关性；3）视网膜静脉病理性鞘膜形成的相对高发生率；4）在有明确复发和缓解的病例中，大脑半球阴影斑块的比例较高。
