Horwitz C, Rozen P, Gilat T
Nutr Cancer. 1983;5(1):51-4. doi: 10.1080/01635588309513778.
Estrogens and compounds with estrogenic activity have been used for many years as animal growth promoters and to synchronize estrus in cows. The resorcylic acid lactones (RALS), which include zearalenone, are being used increasingly for these purposes. These estrogenic mycotoxins, now produced commercially, have teratogenic, mutagenic, and carcinogenic properties. There is some evidence that their residues could remain in certain organs at the time the animal products come to market, and this may be of medical significance.
雌激素及具有雌激素活性的化合物多年来一直被用作动物生长促进剂以及母牛发情同步剂。包括玉米赤霉烯酮在内的间苯二酚类内酯(RALS)正越来越多地用于这些目的。这些具有雌激素活性的霉菌毒素如今已实现商业化生产,具有致畸、致突变和致癌特性。有证据表明,在动物产品上市时,它们的残留物可能会残留在某些器官中,这可能具有医学意义。